PURPOSE To assess the efficacy of the tract embolization technique using gelatin sponge slurry after CT-guided lung biopsy to reduce pneumothorax and chest tube placement rates. MATERIALS AND METHODS We retrospectively compared 231 CT-guided lung biopsies performed with the tract embolization technique using gelatin sponge slurry (treated group) with 213 biopsies performed without embolization (control group). All procedures were performed at our institution between January 2014 and September 2018 by one of three experienced interventional radiologists using a 19-gauge coaxial needle. Multivariate analysis was performed between groups for risk factors for pneumothorax and chest tube placement, including patient demographics and lesion characteristics. RESULTS When comparing the two groups, there was no significant difference concerning age, gender, emphysema, lesion size, lesion location, lesion morphology, needle tract depth and biopsy-side down patient positioning. Compared to the control group, patients with gelatin sponge slurry tract embolization had statistically lower rates of pneumothorax (10% vs. 25.8%; p < 0.0001) and chest tube placement (3.5% vs. 12.2%; p = 0.0005). Using multiple logistic regression analysis, the only variable that had an influence on the pneumothorax rate was the group (OR 0.32, 95% CI 0.18-0.56, p < 0.0001), and the variables that had an influence on the chest tube insertion rates were the group (OR 0.21, 95% CI 0.08-0.51, p = 0.0006) and presence of emphysema (OR 3.50, 95% CI 1.53-8.03, p = 0.0031). CONCLUSIONS Tract embolization technique using gelatin sponge slurry after percutaneous CT-guided lung biopsy significantly reduces pneumothorax and chest tube placement rates. LEVEL OF EVIDENCE Level 3a.

中文翻译：

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用明胶海绵浆液栓塞术减少经皮CT引导的肺活检后气胸和胸管放置的功效。

目的评估在CT引导下的肺活检后使用明胶海绵浆液以减少气胸和胸管放置率的管道栓塞技术的疗效。材料与方法我们回顾性地比较了使用明胶海绵浆液（治疗组）和采用血管栓塞技术的231例CT引导下的肺活检（未治疗组）与未栓塞的213例活检。在2014年1月至2018年9月期间，我们的所有程序均由三名经验丰富的介入放射科医生中的一名使用19号同轴针进行。各组之间进行了多因素分析，以分析气胸和胸管放置的危险因素，包括患者的人口统计学特征和病变特征。结果比较两组时，年龄，年龄，性别，肺气肿，病变大小，病变位置，病变形态，针道深度和活检面朝下放置患者。与对照组相比，明胶海绵浆体栓塞患者的气胸发生率（10％比25.8％； p <0.0001）和胸管放置率（3.5％vs. 12.2％； p = 0.0005）在统计学上较低。使用多元逻辑回归分析，唯一影响气胸发生率的变量是组（OR 0.32，95％CI 0.18-0.56，p <0.0001），而影响胸管插入率的变量是组（OR 0.21，95％CI 0.08-0.51，p = 0.0006）和存在肺气肿（OR 3.50，95％CI 1.53-8.03，p = 0.0031）。结论经明胶CT引导的肺活检后，使用明胶海绵浆栓塞术可显着降低气胸和胸管放置率。证据级别3a。