Parkinson's disease (PD) is a progressing neurodegenerative disease predominantly involving the loss of dopamine producing neurons with hallmark symptoms of motor disorders and cognitive, motivational, emotional, and perceptual impairments. Intriguingly, PD can also be connected-often anecdotally-with a sudden burst of artistic creativity, motivation, or changed quality/style of produced art. This has led to growing empirical interest, promising a window into brain function and the unique neurological signature of artists. This topic also fits a growing interest from researchers in other areas, including Alzheimer's or other dementia, which have suggested that specific changes in art production/appraisal may provide a unique basis for therapy, diagnosis, or understanding of these diseases. However, whether PD also shows similar impacts on how we perceive and evaluate art has never been systematically addressed. We compared a cohort of PD patients against age-matched healthy controls, asking participants to rate paintings using scales of liking and beauty and terms pertaining to artworks' formal and conceptual qualities previously designed to provide a rubric for symptom identification. We found no evidence for PD-related differences in liking or beauty. However, PD patients showed higher ratings on assessed "emotionality," potentially relating to the tie between PD, dopamine pathways, and emotion/reward.

中文翻译：

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帕金森氏病和艺术欣赏的变化：PD患者与健康对照者对绘画的审美和形式评价的比较。

帕金森氏病（PD）是一种进行性神经退行性疾病，主要涉及多巴胺产生性神经元的丧失，这些神经元具有运动障碍和认知，动机，情感和知觉障碍的明显症状。有趣的是，PD也可能经常与艺术创作，动力或生产艺术品的质量/风格突然爆发有关。这引起了越来越多的经验兴趣，为了解脑功能和艺术家独特的神经学特征开辟了一个窗口。这个话题也符合包括阿尔茨海默氏病或​​其他痴呆症在内的其他领域的研究人员的日益增长的兴趣，这些领域的研究人员提出，艺术品生产/评估的特定变化可能为治疗，诊断或了解这些疾病提供独特的基础。然而，PD是否也会对我们对艺术的感知和评估产生类似影响，这一点从未得到系统地解决。我们将一组PD患者与年龄匹配的健康对照组进行了比较，要求参与者使用喜欢和美丽的等级以及与艺术品的形式和概念品质有关的术语对绘画进行评分，这些术语以前旨在为症状识别提供参考。我们没有发现与PD相关的喜好或美容差异的证据。然而，PD患者对评估的“情绪”表现出较高的评分，这可能与PD，多巴胺途径和情绪/奖励之间的联系有关。要求参加者使用喜欢和美丽的等级以及与艺术品的形式和概念品质有关的术语对绘画进行评分，这些术语以前旨在为症状识别提供参考。我们没有发现与PD相关的喜好或美容差异的证据。但是，PD患者对评估的“情绪”表现出较高的评分，这可能与PD，多巴胺途径和情绪/奖励之间的联系有关。要求参加者使用喜欢和美丽的等级以及与艺术品的形式和概念品质有关的术语对绘画进行评分，这些术语以前旨在为症状识别提供参考。我们没有发现与PD相关的喜好或美容差异的证据。但是，PD患者对评估的“情绪”表现出较高的评分，这可能与PD，多巴胺途径和情绪/奖励之间的联系有关。