Near-infrared spectroscopy (NIRS) has become an increasingly valuable tool to monitor tissue oxygenation (Toxy) in vivo. Observations of changes in the absorption of light with Toxy have been recognized as early as 1876, leading to a milestone NIRS paper by Jöbsis in 1977. Changes in the absorption and scatting of light in the 700-850-nm range has been successfully used to evaluate Toxy. The most practical devices use continuous-wave light providing relative values of Toxy. Phase-modulated or pulsed light can monitor both absorption and scattering providing more accurate signals. NIRS provides excellent time resolution (~ 10 Hz), and multiple source-detector pairs can be used to provide low-resolution imaging. NIRS has been applied to a wide range of populations. Continued development of NIRS devices in terms of lower cost, better detection of both absorption and scattering, and smaller size will lead to a promising future for NIRS studies.

中文翻译：

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近红外光谱学的早期发展回顾及肌肉氧合和氧化代谢研究的最新进展。


近红外光谱 (NIRS) 已成为监测体内组织氧合 (Toxy) 的越来越有价值的工具。早在 1876 年，Toxy 对光吸收变化的观察就已得到认可，Jöbsis 于 1977 年发表了具有里程碑意义的 NIRS 论文。700-850 nm 范围内光吸收和散射的变化已成功用于评估托克西。最实用的设备使用连续波光来提供 Toxy 的相对值。相位调制或脉冲光可以监测吸收和散射，提供更准确的信号。 NIRS 提供出色的时间分辨率（~ 10 Hz），并且可以使用多个源-探测器对来提供低分辨率成像。 NIRS 已应用于广泛的人群。 NIRS 设备在更低的成本、更好的吸收和散射检测以及更小的尺寸方面的持续发展将为 NIRS 研究带来光明的未来。