Bimanual skills are important for goal-oriented activities. Children with unilateral cerebral palsy (UCP) have deficits in unimanual and bimanual motor control and learning. The application of non-invasive brain stimulation with existing motor training may further promote motor learning; however, the effects of stimulation on bimanual learning have not been examined. Here, we assessed the performance of a novel bimanual skill (modified Speed Stacks task) in eight children with UCP before, during, and after a combined motor training and brain stimulation intervention. Participants received 10 days (120 min/day) of goal-oriented bimanual therapy combined initially with transcranial direct current stimulation (tDCS, 20 min/day). Results showed task improvement tapered (p < 0.001) during and after the intervention and task variability decreased in 6/8 participants, indicating the potential impact of novel rehabilitation to improve skill learning in children with UCP. Future work is required to understand how both tDCS and bimanual training contribute to learning bimanual tasks.

双向技能对于面向目标的活动很重要。单侧脑瘫（UCP）的儿童在单手和双手运动控制和学习方面存在缺陷。在现有的运动训练中应用无创性脑刺激可以进一步促进运动学习。但是，尚未研究刺激对双手学习的影响。在这里，我们评估了运动训练和脑刺激干预相结合之前，之中和之后，八名UCP儿童的一项新的双向技能（改进的Speed Stacks任务）的表现。参与者最初接受经颅直流电刺激（tDCS，20分钟/天），然后接受了10天（120分钟/天）的目标导向的双手疗法。结果显示任务改进呈锥形（p <0。001）在干预期间和之后以及6/8参与者中任务可变性降低，表明新型康复对改善UCP儿童的技能学习有潜在影响。需要进一步的工作来了解tDCS和双向培训如何有助于学习双向任务。