PURPOSE Fluid-attenuated inversion recovery vascular hyperintensity (FVH) is frequently found in stroke patients after intracranial arterial occlusion, but the prognostic value of FVH findings is unclear. We assessed whether FVH is associated with cerebral collateral status and functional outcome in patients with acute stroke patients receiving endovascular therapy. METHODS FVH score, American Society of Interventional and Therapeutic Neuroradiology (ASITN) grade, the functional outcome at 3 months (modified Rankin Scale (mRS)), and other clinical data were collected for 37 acute stroke patients with large vessel occlusion (LVO) receiving MRI before and after endovascular therapy. Statistical analysis was performed to predict functional outcome after stroke. RESULTS The good functional outcome group (n = 16) had a higher FVH1 (FVH before therapy) score (4.63 ± 1.20 vs 3.14 ± 1.15; p = 0.001) and ASITN grade (3.31 ± 0.48 vs 2.00 ± 1.22; p < 0.001) and a lower FVH2 (FVH after therapy) score than the poor functional outcome group (n = 21; 0.125 ± 0.50 vs 1.44 ± 2.16; p = 0.030). mRS at 3 months was negatively correlated with FVH1 (r = - 0.525, p = 0.001) and the ASITN grade (r = - 0.478, p = 0.003) and positively correlated with FVH2 (r = 0.376, p = 0.034). FVH1 (OR, 0.085; 95% CI, 0.013-0.577; p = 0.012) and FVH2 (OR, 2.724; 95% CI, 1.061-6.996; p = 0.037) were independently associated with functional outcome in multivariable logistic regression analysis. CONCLUSIONS Assessing FVH before and after therapy in acute stroke patients with LVO might be useful for predicting functional outcome after stroke. KEY POINTS • Fluid-attenuated inversion recovery vascular hyperintensity is a circular or serpentine brightening in the brain parenchyma or cortical surface bordering the subarachnoid space on MR imaging. • A prospective study showed that fluid-attenuated inversion recovery vascular hyperintensity is associated with cerebral collateral circulation and prognosis. • Fluid-attenuated inversion recovery vascular hyperintensity helps clinicians to predict the prognosis of patients with acute stroke.

中文翻译：

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急性中风的FLAIR血管高血压与抵押和功能预后相关。

目的颅内动脉闭塞后脑卒中患者中经常发现体液衰减型反转恢复血管高强度（FVH），但尚不清楚FVH的预后价值。我们评估了接受血管内治疗的急性中风患者的FVH是否与脑侧支状态和功能结局相关。方法收集了37例接受大血管闭塞（LVO）的急性卒中患者的FVH评分，美国介入治疗神经放射学会（ASITN）等级，3个月的功能结局（改良的Rankin量表（mRS））和其他临床数据。血管内治疗前后的MRI。进行统计分析以预测中风后的功能结局。结果良好的功能结局组（n = 16）的FVH1（治疗前FVH）评分较高（4.63±1.20 vs 3.14±1.15; p = 0.001）和ASITN评分（3.31±0.48 vs 2.00±1.22; p <0.001）并且功能不良转归组的FVH2（治疗后FVH）得分较低（n = 21； 0.125±0.50 vs 1.44±2.16； p = 0.030）。3个月时的mRS与FVH1呈负相关（r =-0.525，p = 0.001）和ASITN等级（r =-0.478，p = 0.003）呈负相关，与FVH2正相关（r = 0.376，p = 0.034）。在多变量逻辑回归分析中，FVH1（OR，0.085; 95％CI，0.013-0.577; p = 0.012）和FVH2（OR，2.724; 95％CI，1.061-6.996; p = 0.037）独立地与功能结局相关。结论对急性卒中LVO患者治疗前后进行FVH评估可能有助于预测卒中后的功能结局。要点•液体衰减型反转恢复血管高强度是在MR影像学上邻近蛛网膜下腔的脑实质或皮质表面的圆形或蛇形增亮。•一项前瞻性研究表明，液体衰减型反转恢复血管高强度与脑侧支循环和预后相关。•液体衰减型倒置恢复血管过度紧张有助于临床医生预测急性中风患者的预后。•一项前瞻性研究表明，液体衰减型反转恢复血管高强度与脑侧支循环和预后相关。•液体衰减型倒置恢复血管过度紧张有助于临床医生预测急性中风患者的预后。•一项前瞻性研究表明，液体衰减型反转恢复血管高强度与脑侧支循环和预后相关。•液体衰减型倒置恢复血管过度紧张有助于临床医生预测急性中风患者的预后。