OBJECTIVE Fine needle aspiration (FNA) is a minimally invasive albeit highly effective modality used to detect solid and cystic pancreatic lesions. This manuscript aims to present our experience in diagnosing metastases to the pancreas and highlight the importance of immunocytochemistry in the diagnostic process. It also aims to provide a brief review of the literature on this topic. METHODS We retrospectively searched our archives for cases of metastatic deposits to the pancreas diagnosed with FNA over a 5-year period. We also reviewed the literature for such cases. RESULTS We describe seven cases from our archives that metastasised to the pancreas. Three of them (43%) represented metastatic renal cell carcinoma while the rest four comprised deposits from a lung adenocarcinoma, a colon adenocarcinoma, an adrenal leiomyosarcoma, and a small cell carcinoma of the urinary bladder, respectively. History of primary malignancy was available for all seven patients. All diagnoses were confirmed with the use of immunostains. In our literature review, similar to our case series, renal cell carcinoma was the most common metastasis to the pancreas managed with FNA (around one out of three patients; 35%). Of interest, our endoscopic ultrasound-FNA case of pancreatic metastasis from urinary bladder small cell carcinoma is the first reported. CONCLUSIONS As metastases to the pancreas are commonly accompanied by diverse prognostic signatures and management strategies compared to primary pancreatic malignancies, their accurate identification is imperative. Pancreatic FNA is a diagnostic modality that can confirm or exclude metastasis to the organ, especially when immunocytochemistry is applied.

中文翻译：

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细针穿刺术评估胰腺转移灶：来自单个中心的病例系列并回顾了文献。

目的细针穿刺术（FNA）是一种微创手术，尽管它是一种用于检测实体和囊性胰腺病变的高效方法。该手稿旨在介绍我们在诊断胰腺转移灶方面的经验，并强调免疫细胞化学在诊断过程中的重要性。它还旨在对有关此主题的文献进行简要回顾。方法我们回顾性研究了在档案中5年内诊断为FNA的胰腺转移性沉积物的病例。我们还回顾了此类案例的文献。结果我们描述了从档案中转移到胰腺的七个病例。其中三个（43％）代表转移性肾细胞癌，而其余四个则来自肺腺癌，结肠腺癌，肾上腺平滑肌肉瘤，和膀胱小细胞癌。所有七名患者均具有原发恶性肿瘤的病史。所有诊断均通过使用免疫染色得到证实。在我们的文献综述中，与我们的病例系列相似，肾细胞癌是经FNA处理的胰腺最常见的转移灶（大约三分之一； 35％）。有趣的是，我们的内镜超声-FNA病例是膀胱小细胞癌胰腺转移的首次报道。结论由于与原发性胰腺恶性肿瘤相比，胰腺转移通常伴有多种预后特征和治疗策略，因此必须准确识别。胰腺FNA是一种可以确认或排除器官转移的诊断方法，