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Energy metabolism of follicular environment during oocyte growth and maturation
Journal of Reproduction and Development ( IF 1.9 ) Pub Date : 2020-01-01 , DOI: 10.1262/jrd.2019-102
Ewelina Warzych 1 , Paulina Lipinska 1
Affiliation  

Oocyte quality is affected by many factors, among which the environment of growth and maturation seems to be crucial. Studies show that well balanced oocyte energy metabolism has a significant impact on several elements of cytoplasmic and nuclear maturation as well as further embryo developmental competence. Therefore homeostasis between metabolism of glucose and fatty acids in the oocyte is being widely described nowadays. This review aims to discuss the follicular (in vivo) or maturation media (in vitro) environments with regard to glucose and fatty acid metabolism, as the main sources of the energy for the oocyte. A great emphasis is given on the balance between those two metabolic pathways and its further impact on female fertility.

中文翻译:

卵母细胞生长和成熟过程中卵泡环境的能量代谢

卵母细胞的质量受多种因素影响,其中生长和成熟的环境似乎至关重要。研究表明,平衡良好的卵母细胞能量代谢对细胞质和核成熟的几个要素以及进一步的胚胎发育能力具有显着影响。因此,当今广泛描述了卵母细胞中葡萄糖和脂肪酸代谢之间的稳态。本综述旨在讨论作为卵母细胞主要能量来源的葡萄糖和脂肪酸代谢的卵泡(体内)或成熟培养基(体外)环境。非常重视这两种代谢途径之间的平衡及其对女性生育能力的进一步影响。
更新日期:2020-01-01
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