PURPOSE The aim of this study was to determine the preliminary efficacy and safety of a novel technique for trabeculotomy for the treatment of primary congenital glaucoma (PCG). METHODS This retrospective interventional study was conducted on patients with PCG. Pliability test was performed among 5/0 and 6/0 polypropylene sutures and the flexible illuminated microcatheter. Viscocanalostomy was first performed and the Schlemm's canal was identified. Then, suture trabeculotomy was completed except the region for viscocanalostomy. The preoperative and follow-up data were recorded and analyzed. Success criteria were defined as intraocular pressure (IOP) ≤ 21 mmHg without (complete success) or with medications (qualified success). RESULTS 5/0 polypropylene suture was an appropriate option for cannulation of Schlemm's canal. A total of 33 eyes from 23 consecutive patients were included with a mean follow-up of 9.3 ± 3.6 months (range 6-18 months). Circumferential cannulation by suture was successfully performed in 28 eyes (84.8%) of 18 patients. Mean IOP decreased from 33.9 ± 9.4 mmHg preoperatively to 10.5 ± 3.5 mmHg at 6 months (p < 0.001) and 11.3 ± 4.1 mmHg at 9 months (p < 0.001). Complete success rate was 92.9% [95% confidence interval (CI:0.83-1.03)] and 87.5% (CI:0.69-1.06) at 6 months and 9 months, respectively. Hyphema was found in 5 eyes (17.9%), all of which were absorbed within 1 week. No other complications were observed. CONCLUSIONS Viscocanalostomy combined with nearly 360-degree suture trabeculotomy as a novel technique controls IOP in patients with PCG without any severe complications. It is suitable for extended applications because of accurate identification of Schlemm's canal and low cost.

中文翻译：

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粘膜吻合口吻合术近360度缝合小梁切开术治疗原发性先天性青光眼：新型小梁切开术技术的初步报道。

目的本研究的目的是确定小梁切除术治疗原发性先天性青光眼（PCG）的新技术的初步疗效和安全性。方法这项回顾性干预研究是针对PCG患者进行的。在5/0和6/0聚丙烯缝合线和柔性照明微导管之间进行了柔韧性测试。首先进行粘膜吻合口吻合术，并确定Schlemm管。然后，完成缝合小梁切开术，除了粘膜吻合口切开术的区域。记录并分析术前和随访数据。成功标准被定义为眼压（IOP）≤21 mmHg，无（完全成功）或有药物（合格成功）。结果5/0聚丙烯缝合线是施莱姆管插管的合适选择。纳入了来自连续23例患者的33只眼，平均随访9.3±3.6个月（6-18个月）。18例患者的28眼（84.8％）成功地通过缝合进行了环周插管。平均IOP从术前的33.9±9.4 mmHg降至6个月时的10.5±3.5 mmHg（p <0.001）和9个月时的11.3±4.1 mmHg（p <0.001）。在6个月和9个月时，完全成功率分别为92.9％[95％置信区间（CI：0.83-1.03）]和87.5％（CI：0.69-1.06）。在5只眼中发现前房积血（17.9％），所有这些均在1周内被吸收。没有观察到其他并发症。结论粘膜吻合口吻合术与近360度缝合小梁切开术相结合是一种控制PCG患者IOP的新技术，无任何严重并发症。