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Resistant starch: impact on the gut microbiome and health.
Current Opinion in Biotechnology ( IF 7.1 ) Pub Date : 2019-11-22 , DOI: 10.1016/j.copbio.2019.10.008
Peter DeMartino 1 , Darrell W Cockburn 1
Affiliation  

Resistant starch has received a lot of attention for its potential to exert a healthy impact on the gut and certain members of its resident microbiota, particularly through enhanced butyrate production. However, resistant starch is a broad category that encompasses several structurally different starches. While all resist digestion by human enzymes, they differ in their effects on the microbiota. Individual variation in microbiota composition also has a substantial influence on butyrate production. Research on this interaction between resistant starch and the microbiota is using in vitro fermentations, cross-over design clinical trials and mouse studies with isotopically labeled starch. These studies are demonstrating that more personalized approaches are needed for finding resistant starch or other fiber that will promote a healthy gut.

中文翻译:

抗性淀粉:影响肠道微生物组和健康。

抵抗性淀粉具有对肠道及其常驻菌群某些成员产生健康影响的潜力,尤其是通过提高丁酸酯的产量而受到广泛关注。但是,抗性淀粉是广泛的类别,涵盖了几种结构上不同的淀粉。尽管所有人都抵抗人类酶的消化,但是它们对微生物群的作用不同。微生物群组成的个体变化也对丁酸盐的产生具有重大影响。关于抗性淀粉与微生物群之间这种相互作用的研究,是利用体外发酵,交叉设计临床试验以及同位素标记淀粉进行的小鼠研究。这些研究表明,需要更多个性化的方法来寻找抗性淀粉或其他可促进肠道健康的纤维。
更新日期:2019-11-01
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