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Acute phase response and clinical manifestation in outbreaks of interdigital phlegmon in dairy herds.
Comparative Immunology, Microbiology and Infectious Diseases ( IF 2 ) Pub Date : 2019-10-31 , DOI: 10.1016/j.cimid.2019.101375
Miia Kontturi 1 , Reijo Junni 1 , Minna Kujala-Wirth 1 , Erja Malinen 2 , Eija Seuna 2 , Sinikka Pelkonen 2 , Timo Soveri 1 , Heli Simojoki 1
Affiliation  

Several Finnish dairy herds have suffered from outbreaks of interdigital phlegmon (IP). In these new types of outbreaks, morbidity was high and clinical signs severe, resulting in substantial economic losses for affected farms. In our study, we visited 18 free stall dairy herds experiencing an outbreak of IP and 3 control herds without a similar outbreak. From a total of 203 sampled cows, 60 suffered from acute stage IP. We demonstrated that acute phase response of bovine IP was evident and therefore an appropriate analgesic should be administered in the treatment of affected animals. The response was most apparent in herds with high morbidity in IP and with a bacterial infection comprising Fusobacterium necrophorum and Dichelobacter nodosus, indicating that combination of these two bacterial species affect the severity of the disease.

中文翻译:

乳牛群中叉指化痰菌暴发的急性期反应和临床表现。

数只芬兰奶牛场遭受了指间弗氏菌(IP)的暴发。在这些新的暴发类型中,发病率很高,临床症状很严重,给受影响的农场造成了巨大的经济损失。在我们的研究中,我们访问了18个出现IP疫情的免费摊位奶牛群和3个没有类似疫情的对照牛群。在总共203头奶牛中,有60头患有IP急性期。我们证明了牛IP的急性期反应是明显的,因此在治疗患病动物时应给予适当的镇痛药。该反应在IP发病率高的猪群和包括坏死镰刀菌和结节双歧杆菌的细菌感染中最为明显,表明这两种细菌的​​组合会影响疾病的严重程度。
更新日期:2019-11-01
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