PURPOSE This study analysed nutritional parameters (baseline body mass index (BMI), weight changes and enteral nutrition (EN) use, and their association with hospital admissions during radiotherapy in patients with head and neck cancer (HNC)). METHODS A retrospective review of patients diagnosed with HNC and treated with radiotherapy between October 2012 and April 2014 was conducted. Data on each subject's diagnosis, age, sex, chemotherapy, previous surgery, EN use, weight changes, and BMI were examined for their association with hospital admissions during treatment. RESULTS Eighty-three patients were included, mean age (±standard deviation) = 61 (± 11 years). Thirty-four percent had self-reported weight loss at diagnosis, and mean BMI was 26.2 ± 5.3 kg/m2. Mean weight change during treatment was - 5.1 ± 6.2%. Ten patients used EN, with mean weight stabilisation during EN use (0.3 ± 5.1%). Higher presenting BMI, younger age, and definitive radiotherapy ± chemotherapy predicted greater weight loss (p < 0.05). Critical weight loss ≥ 5% was associated with a higher number of hospital admissions for nutrition reasons (n = 10) (p = 0.011) compared with those without critical weight loss (n = 2). EN use was associated with a higher number of nutrition-related admissions; however, it did not predict length of stay among those admitted. CONCLUSION Critical weight loss during radiotherapy was associated with unplanned nutrition-related hospital admissions. Higher BMI was associated with greater weight loss during radiotherapy, whilst EN use assisted in weight preservation. Further research around patient selection for nutritional interventions aimed at preventing critical weight loss and unplanned hospital admissions is needed.

中文翻译：

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与接受头颈癌治疗的患者入院相关的营养参数。

目的 本研究分析了营养参数（基线体重指数 (BMI)、体重变化和肠内营养 (EN) 的使用，以及它们与头颈癌 (HNC) 患者放疗期间入院的关系）。方法 对 2012 年 10 月至 2014 年 4 月期间诊断为 HNC 并接受放射治疗的患者进行回顾性分析。检查每个受试者的诊断、年龄、性别、化疗、既往手术、EN 使用、体重变化和 BMI 的数据与治疗期间入院的关系。结果 共纳入 83 名患者，平均年龄（±标准差）= 61（± 11 岁）。34% 的人在诊断时自我报告体重减轻，平均 BMI 为 26.2 ± 5.3 kg/m2。治疗期间的平均体重变化为 - 5.1 ± 6.2%。10名患者使用EN，EN 使用期间的平均重量稳定 (0.3 ± 5.1%)。更高的 BMI、更年轻的年龄和明确的放疗±化疗预测更大的体重减轻（p < 0.05）。与没有严重体重减轻的患者（n = 2）相比，严重体重减轻 ≥ 5% 与因营养原因住院的人数（n = 10）（p = 0.011）相关。EN 的使用与更多的营养相关入院相关；但是，它没有预测被录取者的逗留时间。结论 放疗期间严重的体重减轻与计划外的营养相关住院有关。较高的 BMI 与放疗期间较大的体重减轻有关，而 EN 的使用有助于保持体重。