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Transcriptional regulation of chicken leukocyte cell-derived chemotaxin 2 in response to toll-like receptor 3 stimulation.
Animal Bioscience ( IF 2.4 ) Pub Date : 2019-07-02 , DOI: 10.5713/ajas.19.0192
Seokhyun Lee 1 , Ra Ham Lee 1 , Sung-Jo Kim 2 , Hak-Kyo Lee 1 , Chong-Sam Na 1 , Ki-Duk Song 1, 3
Affiliation  

Leukocyte cell-derived chemotaxin 2 (LECT2) is associated with several physiological processes including inflammation, tumorigenesis, and natural killer T cell generation. Chicken LECT2 (chLECT2) gene was originally identified as one of the differentially expressed genes in chicken kidney tissue, where the chickens were fed with different calcium doses. In this study, the molecular characteristics and gene expression of chLECT2 were analyzed under the stimulation of toll-like receptor 3 (TLR3) ligand to understand the involvement of chLECT2 expression in chicken metabolic disorders.

中文翻译:

鸡白细胞衍生的趋化因子2响应toll样受体3刺激的转录调控。

白细胞衍生的趋化因子2(LECT2)与几种生理过程有关,包括炎症,肿瘤发生和自然杀伤性T细胞生成。鸡LECT2(chLECT2)基因最初被鉴定为鸡肾组织中差异表达的基因之一,在鸡肾组织中,给鸡饲喂了不同的钙剂量。在这项研究中,分析了chLECT2的分子特性和基因表达,该模拟是在通行费样受体3(TLR3)配体的刺激下进行的,以了解chLECT2表达与鸡代谢紊乱有关。
更新日期:2020-08-21
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