Polarized exocytosis is generally considered as the multistep vesicular trafficking process in which membrane-bounded carriers are transported from the Golgi or endosomal compartments to specific sites of the plasma membrane. Polarized exocytosis in cells is achieved through the coordinated actions of membrane trafficking machinery and cytoskeleton orchestrated by signaling molecules such as the Rho family of small GTPases. Elucidating the molecular mechanisms of polarized exocytosis is essential to our understanding of a wide range of pathophysiological processes from neuronal development to tumor invasion.

中文翻译：

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极化胞吐作用。

极化胞吐作用通常被认为是多步囊泡运输过程，其中膜结合的载体从高尔基体或内体区室运输到质膜的特定部位。细胞中的极化胞吐作用是通过膜转运机制和信号分子（例如小GTPase的Rho家族）精心策划的细胞骨架的协同作用来实现的。阐明极化胞吐作用的分子机制对于我们理解从神经元发育到肿瘤浸润的各种病理生理过程至关重要。