The prevalence and severity of asthma, particularly the most common (atopic) form of the disease, increase amongst females but not males after puberty, and asthma activity also changes throughout the menstrual cycle and during pregnancy. The contribution of female sex hormones to asthma pathogenesis is incompletely understood.

中文翻译：

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雌激素在实验性哮喘模型中放大预先存在的特应性相关 Th2 偏倚

哮喘的患病率和严重程度，尤其是最常见的（特应性）疾病形式，在青春期后女性而非男性中增加，并且哮喘活动也在整个月经周期和怀孕期间发生变化。女性性激素对哮喘发病机制的贡献尚不完全清楚。