Coxiella burnetii, the etiological agent of Q fever, is a globally distributed zoonotic disease. The disease was reported serologically in different animal species and humans in Egypt but the genetic information about circulating Coxiella strains is limited. The present study aimed to genetically characterize Coxiella positive samples, identified in abortive sheep, based on a 17-loci Multiple Locus Variable number tandem repeat analysis (MLVA) panel and Multispacer Sequence Typing (MST). Four MLVA types were found among six examined samples. While all three samples examined by MST were identified as novel sequence type (ST) closely related to human heart valve isolates from France, Saudi Arabia, USA and United Kingdom. This study provides the first genetic information about circulating Coxiella strains in Egypt and improves epidemiological data of Q fever in the country.

中文翻译：

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来自埃及绵羊的柯氏杆菌的分子分型。

Q热的病原体柯氏杆菌是一种全球分布的人畜共患病。该疾病在埃及的不同动物物种和人类中都有血清学报道，但有关循环柯氏杆菌菌株的遗传信息有限。本研究旨在基于17个位点的多基因座可变数串联重复分析（MLVA）面板和多间隔物序列分型（MST），对流产绵羊中鉴定的Coxiella阳性样品进行遗传表征。在六个检查样本中发现了四种MLVA类型。通过MST检查的所有三个样品均被鉴定为与来自法国，沙特阿拉伯，美国和英国的人心脏瓣膜分离株密切相关的新型序列类型（ST）。