BACKGROUND This prospective study measured body composition based on bioelectrical impedance analysis (BIA) in relation to preoperative and postoperative nutritional support and status in patients undergoing liver surgery. METHODS Thirty-seven patients with impaired liver function (indocyanine green retention rate at 15 min >15%) undergoing hepatectomy for hepatocellular carcinoma or colorectal liver metastasis were enrolled. The control group (n = 10) received no nutritional supplementation. The late-evening snack (LES, n = 26) group received a 210-kcal snack comprising a carbohydrate with branched-chain amino acids for 2 weeks before surgery through to 12 weeks after surgery. BIA of body composition, including body cell mass and skeletal muscle volume, was performed. RESULTS Although there was no sarcopenia based on the consensus report of the Asian Working Group 2 weeks before surgery, the skeletal muscle volumes in the control and LES groups were at the lower limit of the normal range. Body cell mass and skeletal muscle volume were significantly lower in the control group than in the LES group at 4 (p = 0.03) and 12 (p = 0.02) weeks after surgery. CONCLUSION Late-evening carbohydrate and branched-chain amino acid snack supplementation may improve nutritional status in patients with impaired liver function undergoing hepatectomy.

中文翻译：

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基于身体成分的生物电阻抗分析，深夜碳水化合物和支链氨基酸零食改善了接受肝切除术的患者的营养状况。

背景这项前瞻性研究基于生物电阻抗分析 (BIA) 测量了与接受肝脏手术的患者术前和术后营养支持和状态相关的身体成分。方法 纳入因肝细胞癌或结直肠肝转移行肝切除术的肝功能受损（15 min 吲哚菁绿保留率>15%）的 37 例患者。对照组（n = 10）未接受营养补充。深夜点心 (LES, n = 26) 组在手术前 2 周至手术后 12 周期间接受 210 kcal 的零食，其中包含具有支链氨基酸的碳水化合物。进行了身体成分的 BIA，包括身体细胞质量和骨骼肌体积。结果虽然根据亚洲工作组的共识报告，术前2周没有出现肌肉减少症，但对照组和LES组的骨骼肌体积处于正常范围的下限。在手术后 4 (p = 0.03) 和 12 (p = 0.02) 周，对照组的体细胞质量和骨骼肌体积明显低于 LES 组。结论 深夜补充碳水化合物和支链氨基酸零食可以改善接受肝切除术的肝功能受损患者的营养状况。03) 和 12 (p = 0.02) 周后手术。结论 深夜补充碳水化合物和支链氨基酸零食可以改善接受肝切除术的肝功能受损患者的营养状况。03) 和 12 (p = 0.02) 周后手术。结论 深夜补充碳水化合物和支链氨基酸零食可以改善接受肝切除术的肝功能受损患者的营养状况。