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TMEM106B Effect on Cognition in Parkinson's Disease and Frontotemporal Dementia
Annals of Neurology ( IF 8.1 ) Pub Date : 2019-05-14 , DOI: 10.1002/ana.25486 Thomas F Tropea 1 , Jordan Mak 1 , Michael H Guo 2, 3 , Sharon X Xie 4 , Eunran Suh 5 , Jacqueline Rick 1 , Andrew Siderowf 1 , Daniel Weintraub 6, 7 , Murray Grossman 1 , David Irwin 1 , David A Wolk 1 , John Q Trojanowski 5, 8 , Vivianna Van Deerlin 5 , Alice S Chen-Plotkin 1
Annals of Neurology ( IF 8.1 ) Pub Date : 2019-05-14 , DOI: 10.1002/ana.25486 Thomas F Tropea 1 , Jordan Mak 1 , Michael H Guo 2, 3 , Sharon X Xie 4 , Eunran Suh 5 , Jacqueline Rick 1 , Andrew Siderowf 1 , Daniel Weintraub 6, 7 , Murray Grossman 1 , David Irwin 1 , David A Wolk 1 , John Q Trojanowski 5, 8 , Vivianna Van Deerlin 5 , Alice S Chen-Plotkin 1
Affiliation
Common variants near TMEM106B associate with risk of developing frontotemporal dementia (FTD). Emerging evidence suggests a role for TMEM106B in neurodegenerative processes beyond FTD. We evaluate the effect of TMEM106B genotype on cognitive decline across multiple neurogenerative diseases.
中文翻译：
TMEM106B 对帕金森病和额颞叶痴呆认知的影响
TMEM106B 附近的常见变异与发生额颞叶痴呆 (FTD) 的风险相关。新的证据表明 TMEM106B 在 FTD 以外的神经退行性过程中发挥着作用。我们评估了 TMEM106B 基因型对多种神经生成疾病认知能力下降的影响。
更新日期：2019-05-14
中文翻译：
TMEM106B 对帕金森病和额颞叶痴呆认知的影响
TMEM106B 附近的常见变异与发生额颞叶痴呆 (FTD) 的风险相关。新的证据表明 TMEM106B 在 FTD 以外的神经退行性过程中发挥着作用。我们评估了 TMEM106B 基因型对多种神经生成疾病认知能力下降的影响。
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