Precision medicine, incorporating personalized medicine, is an emerging medical model that holds great promise for improving the prevention, diagnosis and treatment of many diseases. The future success of precision medicine, however, depends on the establishment of large databases that collate diverse data, including family genealogies, disease histories, drug sensitivities and genomic data. Herein I raise some of the social and ethical challenges that such a system faces, specifically: the enrolment of volunteers into large genetic databases; the need for a change in mindset of clinicians, patients and the wider public; and the need for interdisciplinary ethics considering the emerging issues. Finally I argue that the future potential of 'personalized' medicine crucially depends on 'collective' participation of informed citizens.

中文翻译：

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个性化医学的集体性质。

结合个性化医学的精密医学是一种新兴的医学模型，在改善许多疾病的预防，诊断和治疗方面具有广阔的前景。但是，精密医学的未来成功取决于建立大型数据库来收集各种数据，这些数据包括家族谱系，疾病史，药物敏感性和基因组数据。在这里，我提出了这样一个系统所面临的一些社会和道德挑战，特别是：将志愿者纳入大型基因数据库；需要改变临床医生，患者和广大公众的观念；以及考虑新出现问题的跨学科伦理学的需求。最后，我认为，“个性化”医学的未来潜力关键取决于知情公民的“集体”参与。