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Journey of begomovirus betasatellite molecules: from satellites to indispensable partners.
Virus Genes ( IF 1.6 ) Pub Date : 2019-11-27 , DOI: 10.1007/s11262-019-01716-5
Muhammad Mubin 1 , Sehrish Ijaz 1 , Nazia Nahid 2 , Muhammad Hassan 1 , Ayesha Younus 3 , Javaria Qazi 4 , Muhammad Shah Nawaz-Ul-Rehman 1
Affiliation  

Betasatellites are a group of circular, single-stranded DNA molecules that are frequently found to be associated with monopartite begomoviruses of the family Geminiviridae. Betasatellites require their helper viruses for replication, movement, and encapsidation and they are often essential for induction of typical disease symptoms. The βC1 protein encoded by betasatellites is multifunctional that participates in diverse cellular events. It interferes with several cellular processes like normal development, chloroplasts, and innate immune system of plants. Recent research has indicated βC1 protein interaction with cellular proteins and its involvement in modulation of the host's cell cycle and symptom determination. This article focuses on the functional mechanisms of βC1 and its interactions with other viral and host proteins.

中文翻译:

begomovirus betasatellite分子之旅:从卫星到必不可少的伙伴。

Betasatellite是一组圆形的单链DNA分子,通常发现与Geminiviridae家族的单倍子begomoviruses有关。卫星需要其辅助病毒进行复制,移动和衣壳化,它们通常是诱发典型疾病症状所必需的。β卫星编码的βC1蛋白是多功能的,可参与各种细胞事件。它干扰几种细胞过程,例如正常发育,叶绿体和植物的先天免疫系统。最近的研究表明,βC1蛋白与细胞蛋白发生相互作用,并参与宿主细胞周期的调节和症状的确定。本文重点研究βC1的功能机制及其与其他病毒和宿主蛋白的相互作用。
更新日期:2019-11-01
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