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High coverage of polio immunization program in refugees resettling in Denmark. A cross-sectional study of polio serology in newly arrived refugees.
Expert Review of Vaccines ( IF 5.5 ) Pub Date : 2019-12-10 , DOI: 10.1080/14760584.2019.1698953
A M F Hvass 1, 2 , C Wejse 1, 3
Affiliation  

Objectives: Wild poliovirus (WPV) infection has been eliminated in Europe through mass immunization. Resettling refugees may lack immunity and importing WPV through refugees continues to cause concerns.Method: We performed a cross-sectional study to establish the prevalence of poliovirus immunity in children and adult refugees resettling in Aarhus, Denmark. Immunity was evaluated by antibody response for serotypes 1, 2, and 3.Results: The participants in this study counted a total of 475 children and adult refugees aged between 6 months and 76 years and 59% were males. The survey was conducted between 2014 and 2016. Among the refugees, 72% were from Syria, and the rest from Eritrea, Congo, Lebanon, Somalia, Afghanistan, Iran, Iraq, Ethiopia, and Columbia. In the cohort, 27 lacked antibodies against a least one serotype. None of the participants lacked antibodies against all three polio types. Originating from The Horn of Africa, age between 20 and 30 and male gender was associated with lack of immunity.Conclusion: The study found a complete WPV immunity in 94% of recently resettled refugees in Denmark. This study demonstrates a high coverage of the polio immunization program. However, ensuring poliovirus immunity among refugees remains a priority until polio has been eradicated worldwide.

中文翻译:

丹麦定居的难民对小儿麻痹症免疫计划的覆盖率很高。对新近抵达的难民的脊髓灰质炎血清学进行横断面研究。

目的:欧洲已通过大规模免疫消除了脊髓灰质炎病毒(WPV)的感染。定居的难民可能缺乏免疫力,通过难民进口WPV仍然引起人们的关注。方法:我们进行了一项横断面研究,以确定在丹麦奥尔胡斯定居的儿童和成年难民中脊髓灰质炎病毒免疫的情况。通过针对血清型1、2和3的抗体反应评估免疫力。结果:本研究的参与者计算出475名年龄在6个月至76岁之间的儿童和成年难民,其中59%是男性。这项调查是在2014年至2016年之间进行的。在难民中,有72%来自叙利亚,其余的则来自厄立特里亚,刚果,黎巴嫩,索马里,阿富汗,伊朗,伊拉克,埃塞俄比亚和哥伦比亚。在该队列中,有27种缺乏针对至少一种血清型的抗体。没有一个参与者缺乏针对所有三种脊髓灰质炎类型的抗体。起源于非洲之角,年龄在20至30岁之间,并且性别与男性缺乏免疫力有关。结论:该研究发现,在94%的丹麦近期重新安置的难民中,WPV具有完全的免疫力。这项研究证明了脊髓灰质炎免疫计划的高度覆盖。然而,在全世界消灭脊髓灰质炎之前,确保难民中的脊髓灰质炎病毒免疫仍然是一个优先事项。
更新日期:2019-11-01
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