Sociologists have documented how the pharmaceutical industry has corrupted pharmacovigilance (PV), defined as the practices devoted to detecting and preventing adverse drug reactions (ADRs). In this article, I juxtapose the official postmarketing system of PV with firsthand accounts of ADRs as found in 60 YouTube vlogs created by 29 individuals who recount debilitating reactions to fluoroquinolones, a common class of antibiotics. Whereas official PV is said to contribute the banalization of risk, these vlogs exemplify the dramatization of risk. I consider the vlogs as instances of lay PV. They represent lay knowledge claims created in response to perceived failures in the official system of regulation. As such, lay PV shares commonalties with other articulations of lay expertise as a counter to medical authority. At the same time, this case also underscores how the YouTube platform offers new tools for the creation and distribution of lay expertise.

中文翻译：

---

进行药物警戒和风险的剧变：YouTube上的氟喹诺酮危害。

社会学家已经记录了制药业如何破坏药物警戒性（PV），药物警戒性是指专门用于检测和预防药物不良反应（ADR）的行为。在本文中，我将PV的官方售后系统与ADR的第一手资料并置在一起，这是在29位个人创建的60个YouTube视频博客中发现的，这些视频重新描述了对常见的一类氟喹诺酮类药物的反应。据说官方PV助长了风险的泛滥，但这些博客却充分说明了风险的戏剧化。我认为vlog是非专业PV的实例。它们代表为响应官方监管体系中的感知失败而创建的非专业知识主张。因此，非专业PV与其他非专业知识的表达方式具有共同点，以对抗医疗权威。与此同时，