that is likely to expedite identification of malleable early risk factors is increasing the routine collection of a core set of PROMs at diagnosis and continuing periodically throughout the course of epilepsy from early childhood into adulthood. Several PROMs are now available for use in children with epilepsy, and, to guide decisions on choice of measures, there is an emerging literature evaluating the measures’ robustness. Such routine, standardized assessment of PROMs integrated into clinical care is a critical element in determining the quality of data collected, including the amount of attrition, which is essential to the success of longitudinal studies. As researchers increasingly adopt methodological innovations such as those noted above, there will be more robust conclusions on long-term outcomes associated with childhood-onset epilepsy and how to positively affect patients’ outcome trajectories.

中文翻译：

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儿科癫痫和抑郁症的远景

有可能加快识别可延展性早期风险因素的方法是在诊断时增加一组核心 PROM 的常规收集，并在从幼儿期到成年期的整个癫痫病程中定期收集。现在有几种 PROM 可用于癫痫儿童，并且为了指导对措施选择的决定，有新的文献评估了这些措施的稳健性。这种将 PROM 纳入临床护理的常规、标准化评估是确定所收集数据质量的关键因素，包括损耗量，这对纵向研究的成功至关重要。随着研究人员越来越多地采用上述方法创新，