Purpose: The purposes of this study were to investigate upper extremity function and shoulder position sense in patients with multiple sclerosis and its relation with disability level. Materials and methods: In this study, 20 multiple sclerosis and 20 healthy subjects participated. The disability level was determined by the Expanded Disability Status Scale. Mental state was assessed using the Mini-Mental State Examination. Upper extremity function was measured with the 9-Hole Peg Test and shoulder position sense was evaluated with a Dualer IQTM digital inclinometer. The study protocol was also registered at http://clinicaltrials.gov (NCT03846336). Results: Upper extremity function scores were lower and shoulder position sense error scores were greater in patients with multiple sclerosis in comparison to healthy controls (p < .05). While disability level was associated with dominant and non-dominant upper extremity function, no relationship was found between the disability level and shoulder position sense (p < .05). Only the dominant side shoulder position senses at 30° and 60° abduction were found to be associated with upper extremity function (p < .05). Conclusions: These results indicate that shoulder position sense and upper extremity function were affected in patients with multiple sclerosis with mild to moderate disability. Upper extremity functions were associated with shoulder abduction joint sense in patients with multiple sclerosis. In the assessment of upper extremity functions, joint position sense should be taken into account even at early stages of multiple sclerosis, so it may provide guidance in planning rehabilitation programs.

中文翻译：

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多发性硬化症患者上肢功能的研究及其与肩部位置感和残疾水平的关系。

目的：本研究的目的是研究多发性硬化症患者的上肢功能和肩部位置感及其与残疾水平的关系。材料和方法：在这项研究中，20多发性硬化症和20健康受试者参加。残疾水平由扩展的残疾状况量表确定。使用迷你精神状态检查评估精神状态。上肢功能通过9孔钉测试进行测量，肩部位置感通过Dualer IQTM数字测斜仪进行评估。该研究方案也已在http://clinicaltrials.gov（NCT03846336）上注册。结果：与健康对照组相比，多发性硬化症患者的上肢功能评分较低，肩部位置错误评分较高（p <.05）。尽管残疾水平与显性和非显性上肢功能相关，但在残疾水平与肩部位置感之间未发现任何相关性（p <.05）。发现只有在30°和60°外展时的优势侧肩位置感觉与上肢功能有关（p <.05）。结论：这些结果表明，轻度至中度残疾的多发性硬化症患者的肩部位置感和上肢功能受到影响。多发性硬化症患者的上肢功能与肩关节外展感相关。在评估上肢功能时，即使在多发性硬化症的早期也应考虑关节位置感，因此可以为规划康复计划提供指导。