BACKGROUND Scoliosis with spondylolisthesis was described in 4.4-48%. No information on clinical impact or outcome is available. PURPOSE To determine the prevalence of this pathology and to investigate its affect on the course of adolescent idiopathic scoliosis (AIS). METHODS A retrospective comparative study using patients' records, radiographs, the national inpatient registry, and Patient-rated outcome measures (PROM): Oswestry disability index (ODI), modif.SRS-24 questionnaire, WHO-Quality of life index (WHOQoL), Numerical rating scale (NRS) for pain. Clinical follow-up time was 4.4 (4.3) years, and follow-up rate was 95%. PROM follow-up time 26.4 (2.8) years χ2 statistics and t-tests were applied. Significance threshold was set at P < 0.05. RESULTS Out of 1531 consecutive Caucasian AIS patients, aged 13.9 (1.8) years, primary curve 29.2 (11.5) drs., 120 (7.8%) had low-grade isthmic L5-slip of mean 15.0 (8.3)% (Study group = S). The distribution of the curve types in the study group was comparable to the remaining 1411 patients with AIS only. In comparison with a pair-matched control group (C) at admission, back pain interfering with activities of daily living had 4.2% of the study group and 1.7% of the control group, at clinical follow-up 2.6/4.2% resp. (n.s.). Between groups S/C, there was no significant difference concerning scoliosis treatment: observation 38.3/45.8%, bracing 48.3/46.6%, surgery 10.8/10.2%. Results of treatment were equal in both groups. Long-term outcomes (ODI, SRS-24, WHOQoL, NRS-back/leg pain) were comparable. CONCLUSIONS The prevalence of low-grade isthmic L5-spondylolisthesis in AIS patients was 7.8%. The presence of low-grade isthmic spondylolisthesis did not influence the curve type of AIS nor did it affect the course or long-term outcome. These slides can be retrieved under Electronic Supplementary Material.

中文翻译：

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伴随的低度等距性L5腰椎滑脱不影响青少年特发性脊柱侧弯的病程。

背景技术脊柱侧弯伴腰椎滑脱的发生率在4.4％至48％之间。没有有关临床影响或结果的信息。目的确定这种病的患病率，并调查其对青少年特发性脊柱侧凸（AIS）病程的影响。方法回顾性比较研究，使用患者记录，X线照片，国家住院登记表和患者评分结局指标（PROM）：Oswestry残疾指数（ODI），修改后的SRS-24问卷，WHO生活质量指数（WHOQoL） ，疼痛的数字量表（NRS）。临床随访时间为4.4（4.3）年，随访率为95％。PROM随访时间26.4（2.8）年进行了χ2统计和t检验。显着性阈值设置为P <0.05。结果在1531名连续的白种人AIS患者中，年龄为13.9（1.8）岁，初级曲线29.2（11.5）博士，120（7.8％）的低等级L5滑移平均为15.0（8.3）％（研究组= S）。在研究组中，曲线类型的分布仅与其余1411例AIS患者相当。与入院时的配对配对对照组（C）相比，背部疼痛干扰日常生活活动的占研究组的4.2％，占对照组的1.7％，在临床随访中分别为2.6 / 4.2％。（ns）。在S / C组之间，脊柱侧弯的治疗没有显着差异：观察结果38.3 / 45.8％，支撑度48.3 / 46.6％，手术10.8 / 10.2％。两组的治疗结果均相同。长期结果（ODI，SRS-24，WHOQoL，NRS后背/腿痛）具有可比性。结论AIS患者低度等距L5腰椎滑脱的患病率为7.8％。低度峡部峡部滑脱的存在既不影响AIS的曲线类型，也不影响病程或长期预后。这些幻灯片可以在电子补充材料下找到。