Purpose: This study aimed to characterize the sensory profile of patients with post-implant trigeminal neuropathy and identify the association between subjective symptoms and objective signs including psychophysical testing and radiographic imaging. This study further evaluated to the association between quantitative sensory testing (QST)/qualitative sensory testing (QualST) and the severity of nerve injury graded by radiographic imaging. Materials and methods: This retrospective study included 34 patients diagnosed with post-implant trigeminal neuropathy. Data on the neuropathic pain symptom inventory (NPSI), thermal and electric QST, bedside QualST, and cone beam computed tomography (CBCT) was collected and the association between these variables were analysed. Results: Numbness was the most common subjective symptom and evoked pain was the most frequent neuropathic pain. There was no significant correlation between negative and positive symptoms. Spearman's rank correlation analyses indicated that objective findings including QST/QualST correlated with a sensory loss profile rather than a gain of function profile. Moderate positive correlations between some positive symptoms and the score of QualST were observed. The Mann-Whitney U test showed that subjective symptoms did not differ according to the severity of nerve damage according to CBCT, but the electric QST and QualST was discriminative. Conclusions: This study suggests that QST/QualST associated with the severity of nerve damage according to CBCT might be useful in assessing numbness in patients with negative and positive symptoms after implant surgery, but may be of marginal utility in the evaluation of neuropathic pain within the limitation of this cross-sectional study with small sample size.

中文翻译：

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定量和定性的感官测试结果与植入后三叉神经病患者的麻木感相关，而不与神经性疼痛相关：一项横断面先导研究。

目的：本研究旨在表征植入后三叉神经病患者的感觉特征，并确定主观症状与客观体征之间的关联，包括心理物理测试和放射成像。这项研究进一步评估了定量感觉测试（QST）/定性感觉测试（QualST）与X射线影像学分级的神经损伤严重程度之间的关联。材料和方法：这项回顾性研究纳入了34位被诊断为植入后三叉神经病的患者。收集有关神经性疼痛症状清单（NPSI），热和电QST，床旁QualST和锥束计算机断层扫描（CBCT）的数据，并分析这些变量之间的关联。结果：麻木是最常见的主观症状，诱发疼痛是最常见的神经性疼痛。阴性和阳性症状之间无显着相关性。Spearman的等级相关性分析表明，包括QST / QualST在内的客观发现与感觉丧失特征而不是功能获得特征有关。观察到某些积极症状与QualST得分之间存在中等程度的正相关。Mann-Whitney U检验表明，根据CBCT，主观症状不会因神经损伤的严重程度而有所不同，但是电QST和QualST可以区分。结论：