Recent studies indicate hyperuricemia as an aggravating factor for kidney diseases progression. Basic research for novel agents to reduce hyperuricemia and kidney abnormalities will be highly rewarding. Herein, we report Thymoquinone (Tq) as an active constituent of Nigella sativa to have renal protective effective against oxonic acid (OA)‐induced hyperuricemia, hypertension, and renal oxidative stress in rat models.

中文翻译：

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胸腺醌可减轻肾脏线粒体的氧化应激，并在由草酸引起的高尿酸血症大鼠中发挥肾脏保护作用。

最近的研究表明，高尿酸血症是肾脏疾病进展的加重因素。减少高尿酸血症和肾脏异常的新型药物的基础研究将非常有意义。本文中，我们报告胸腺醌（Tq）作为黑变种的有效成分，在大鼠模型中具有对氧酸（OA）引起的高尿酸血症，高血压和肾氧化应激的肾脏保护作用。