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Consensus-based technical recommendations for clinical translation of renal T1 and T2 mapping MRI.
Magnetic Resonance Materials in Physics Biology and Medicine ( IF 2.0 ) Pub Date : 2019-11-22 , DOI: 10.1007/s10334-019-00797-5
Ilona A Dekkers 1 , Anneloes de Boer 2 , Kaniska Sharma 3 , Eleanor F Cox 4 , Hildo J Lamb 1 , David L Buckley 3 , Octavia Bane 5 , David M Morris 6 , Pottumarthi V Prasad 7 , Scott I K Semple 8 , Keith A Gillis 9 , Paul Hockings 10, 11 , Charlotte Buchanan 4 , Marcos Wolf 12 , Christoffer Laustsen 13 , Tim Leiner 2 , Bryan Haddock 14 , Johannes M Hoogduin 2 , Pim Pullens 15, 16 , Steven Sourbron 3 , Susan Francis 2
Affiliation  

To develop technical recommendations on the acquisition and post-processing of renal longitudinal (T1) and transverse (T2) relaxation time mapping. A multidisciplinary panel consisting of 18 experts in the field of renal T1 and T2 mapping participated in a consensus project, which was initiated by the European Cooperation in Science and Technology Action PARENCHIMA CA16103. Consensus recommendations were formulated using a two-step modified Delphi method. The first survey consisted of 56 items on T1 mapping, of which 4 reached the pre-defined consensus threshold of 75% or higher. The second survey was expanded to include both T1 and T2 mapping, and consisted of 54 items of which 32 reached consensus. Recommendations based were formulated on hardware, patient preparation, acquisition, analysis and reporting. Consensus-based technical recommendations for renal T1 and T2 mapping were formulated. However, there was considerable lack of consensus for renal T1 and particularly renal T2 mapping, to some extent surprising considering the long history of relaxometry in MRI, highlighting key knowledge gaps that require further work. This paper should be regarded as a first step in a long-term evidence-based iterative process towards ever increasing harmonization of scan protocols across sites, to ultimately facilitate clinical implementation.

中文翻译:


基于共识的肾脏 T1 和 T2 映射 MRI 临床转化技术建议。



制定有关肾脏纵向 (T1) 和横向 (T2) 弛豫时间图的采集和后处理的技术建议。由 18 名肾脏 T1 和 T2 映射领域的专家组成的多学科小组参与了由欧洲科学技术合作行动 PARENCHIMA CA16103 发起的共识项目。使用两步修改德尔菲法制定了共识建议。第一项调查包含 56 个 T1 映射项目,其中 4 个项目达到了预先定义的 75% 或更高的共识阈值。第二次调查扩大到包括 T1 和 T2 映射,共有 54 项,其中 32 项达成共识。建议是根据硬件、患者准备、采集、分析和报告制定的。制定了基于共识的肾脏 T1 和 T2 标测技术建议。然而,对于肾 T1,特别是肾 T2 映射,人们相当缺乏共识,考虑到 MRI 松弛测量的悠久历史,在某种程度上令人惊讶,突显了需要进一步研究的关键知识差距。本文应被视为长期循证迭代过程的第一步,该过程旨在不断增强跨站点扫描协议的协调性,最终促进临床实施。
更新日期:2019-11-01
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