One of the first characteristics that we learn about the genome of many species is the number of chromosomes it is divided among. Despite this, many questions regarding the evolution of chromosome number remain unanswered. Testing hypotheses of chromosome number evolution using comparative approaches requires trait data to be readily accessible and associated with currently accepted taxonomy. The lack of accessible karyotype data that can be linked to phylogenies has limited the application of comparative approaches that could help us understand the evolution of genome structure. Furthermore, for taxonomists, the significance of new karyotype data can only be determined with reference to records for other species. Here, we describe a curated database (karyotype.org) developed to facilitate access to chromosome number and sex chromosome system data for amphibians. The open web interface for this database allows users to generate customized exploratory plots and tables of selected clades, as well as downloading CSV files for offline analyses.

中文翻译：

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两栖动物核型数据库。

我们了解许多物种的基因组的第一个特征是它划分的染色体数。尽管如此，关于染色体数目演变的许多问题仍未得到解答。使用比较方法测试染色体数目进化的假设要求特征数据易于访问并与当前接受的分类法相关联。缺乏可与系统发育相关的可及的核型数据，限制了可帮助我们了解基因组结构演变的比较方法的应用。此外，对于分类学家而言，只能参考其他物种的记录来确定新核型数据的重要性。在这里，我们描述了一个精选数据库（核型。org）开发来促进两栖动物的染色体数目和性染色体系统数据的访问。该数据库的开放式Web界面使用户可以生成选定进化枝的自定义探索图和表格，以及下载CSV文件以进行离线分析。