Background

In Spain, data of candidemia are limited to surveys conducted in specific areas or tertiary care centers. Also, in recent years, attention has shifted toward episodes of candidemia in non-ICU wards.

Aims

We reviewed the cases of Candida isolates recovered from the blood of patients admitted to the Emergency Room (ER) in our tertiary care hospital.

Methods

The patients selected for this study had an isolation of Candida in the blood culture. All data were collected retrospectively from the clinical records of a 11-year period.

Results

Candida albicans and other species of the genus were present in 10 and 18 patients, respectively. The patients did not present different clinical features in comparison with other reports of hospitalized patients. All patients had several risk factors for candidemia. Only two patients had received previous antifungal therapy before admission. All the isolates of C. albicans, Candida glabrata and the only isolate of Candida tropicalis were susceptible to all the antifungal agents tested. Only one isolate of Candida parapsilosis was susceptible dose-dependent to fluconazole, and the only isolate of Candida metapsilosis was resistant to fluconazole.

Conclusions

It is essential to evaluate the risk factors, underlying conditions and clinical features in non-hospitalized patients in order to determine whether an empirical treatment for candidemia is appropriate.

中文翻译：

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三级医院急诊室患者血液培养中念珠菌的分离。

背景

在西班牙，念珠菌血症的数据仅限于在特定地区或三级护理中心进行的调查。另外，近年来，注意力已转向非ICU病房的念珠菌病发作。

目的

我们审查了从三级医院急诊室（ER）的患者血液中回收的念珠菌分离株的病例。

方法

选择进行这项研究的患者在血液培养中分离出念珠菌。所有数据均从11年的临床记录中回顾性收集。

结果

白色念珠菌和该属的其他物种分别存在于10名和18名患者中。与住院患者的其他报道相比，患者没有表现出不同的临床特征。所有患者都有几种念珠菌血症的危险因素。入院前只有两名患者接受过抗真菌治疗。白色念珠菌，光滑念珠菌和所有热带念珠菌的所有分离株均对所有测试的抗真菌剂敏感。仅一种分离的念珠菌念珠菌对氟康唑具有剂量依赖性，而唯一的念珠菌分离菌对氟康唑具有抗药性。

结论

必须评估非住院患者的危险因素，基本情况和临床特征，以确定是否适合经验性治疗念珠菌血症。