Attention has recently increased in the application of electrospun fibers because of their putative capability to create nanoscale platforms toward tissue engineering. To some extent, electrospun fibers are applicable to the extracellular matrix by providing a three-dimensional microenvironment in which cells could easily acquire definite functional shape and maintain the cell-to-cell connection. It is noteworthy to declare that placement in different electrospun substrates with appropriate physicochemical properties enables cells to promote their bioactivities, dynamics growth and differentiation, leading to suitable restorative effects. This review paper aims to highlight the application of biomaterials in engineered vascular grafts by using electrospun nanofibers to promote angiogenesis and neovascularization.

中文翻译：

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用于制造工程血管移植物的电纺纳米纤维。

最近，静电纺丝纤维的应用受到越来越多的关注，因为它们被认为具有创建组织工程纳米级平台的能力。在某种程度上，电纺纤维可应用于细胞外基质，为细胞提供三维微环境，在该微环境中细胞可以轻松获得明确的功能形状并维持细胞与细胞的连接。值得注意的是，将细胞放置在具有适当理化特性的不同电纺基材中能够促进其生物活性、动态生长和分化，从而产生适当的恢复效果。本文旨在重点介绍生物材料在工程血管移植中的应用，通过使用静电纺丝纳米纤维来促进血管生成和新血管形成。