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The circadian clock control of adipose tissue physiology and metabolism
Autonomic Neuroscience ( IF 2.7 ) Pub Date : 2019-07-01 , DOI: 10.1016/j.autneu.2019.05.001
Damien Lekkas 1 , Georgios K Paschos 1
Affiliation  

The circadian clock organizes the timing of physiological processes in anticipation of diurnal environmental changes that originate from the rotation of the Earth. Several of the metabolic functions of adipose tissues are under regulation by the circadian clock to achieve temporal coordination and whole body homeostasis. Adipose tissues, once believed to only express physiological phenotypes that are downstream of central nervous system regulation, are now well described to communicate not only to other peripheral tissues, but also to the central nervous system for temporal orchestration of metabolism. In this review, we will cover the involvement of the circadian clocks, both master and adipocyte clocks, in the regulation of adipose tissue physiology and the associated consequences for energy homeostasis.

中文翻译:

脂肪组织生理和代谢的生物钟控制

生物钟组织生理过程的时间,以预测源自地球自转的昼夜环境变化。脂肪组织的一些代谢功能受到生物钟的调节,以实现时间协调和全身稳态。脂肪组织,曾经被认为只表达中枢神经系统调节下游的生理表型,现在被很好地描述为不仅可以与其他外周组织交流,还可以与中枢神经系统进行代谢的时间协调。在这篇综述中,我们将介绍生物钟,包括主时钟和脂肪细胞时钟,参与脂肪组织生理学的调节和能量稳态的相关后果。
更新日期:2019-07-01
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