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Interferon-Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non-human primates.
Journal of Medical Primatology ( IF 0.8 ) Pub Date : 2019-05-06 , DOI: 10.1111/jmp.12420 JoAnn L Yee 1 , Kamm Prongay 2 , Brodie Miles 2 , Jeremy Smedley 2 , Scott G Hansen 2 , Michael K Axthelm 2 , Amir Ardeshir 1 , Koen K A Van Rompay 1 , Gregory Timmel 2 , Jeffrey A Roberts 1
Journal of Medical Primatology ( IF 0.8 ) Pub Date : 2019-05-06 , DOI: 10.1111/jmp.12420 JoAnn L Yee 1 , Kamm Prongay 2 , Brodie Miles 2 , Jeremy Smedley 2 , Scott G Hansen 2 , Michael K Axthelm 2 , Amir Ardeshir 1 , Koen K A Van Rompay 1 , Gregory Timmel 2 , Jeffrey A Roberts 1
Affiliation
We have formatted an assay to detect Mycobacterium tuberculosis complex infections of non-human primates. Commercially available reagents were used to elicit a specific immune response that was measured by interferon-gamma release. Initial evaluation using blood samples from Rhesus macaques experimentally infected with M tuberculosis distinguished infected versus uninfected animals.
中文翻译:
干扰素-伽马测试用于检测猕猴和其他非人类灵长类动物中结核分枝杆菌复合群感染。
我们已经制定了一种检测方法来检测非人类灵长类动物的结核分枝杆菌复合感染。市售试剂用于引发特定的免疫反应,该反应通过干扰素-γ 的释放进行测量。使用来自实验感染结核分枝杆菌的恒河猴血液样本的初步评估区分了感染动物与未感染动物。
更新日期:2019-11-01
中文翻译:
干扰素-伽马测试用于检测猕猴和其他非人类灵长类动物中结核分枝杆菌复合群感染。
我们已经制定了一种检测方法来检测非人类灵长类动物的结核分枝杆菌复合感染。市售试剂用于引发特定的免疫反应,该反应通过干扰素-γ 的释放进行测量。使用来自实验感染结核分枝杆菌的恒河猴血液样本的初步评估区分了感染动物与未感染动物。