The spinal cord contains an extraordinarily diverse population of interconnected neurons to process somatosensory information and execute movement. Studies of the embryonic spinal cord have elucidated basic principles underlying the specification of spinal cord neurons, while adult and postnatal studies have provided insight into cell type function and circuitry. However, the overarching principles that bridge molecularly defined subtypes with their connectivity, physiology, and function remain unclear. This review consolidates recent work in spinal neuron characterization, examining how molecular and spatial features of individual spinal neuron types relate to the reference points of connectivity and function. This review will focus on how spinal neuron subtypes are organized to control movement in the mouse.

中文翻译：

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脊髓中的细胞类型和电路模块。

脊髓包含异常多样的相互连接的神经元群，用于处理体感信息和执行运动。胚胎脊髓的研究阐明了脊髓神经元规范的基本原理，而成人和产后研究提供了对细胞类型功能和电路的深入了解。然而，将分子定义的亚型与其连接性、生理学和功能联系起来的总体原则仍不清楚。这篇综述整合了最近在脊髓神经元表征方面的工作，研究了个体脊髓神经元类型的分子和空间特征如何与连接和功能的参考点相关。本综述将重点介绍脊髓神经元亚型如何组织以控制鼠标的运动。