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The chemical logic of plant natural product biosynthesis.
Current Opinion in Plant Biology ( IF 8.3 ) Pub Date : 2014-04-15 , DOI: 10.1016/j.pbi.2014.03.007
Gülbenk Anarat-Cappillino 1 , Elizabeth S Sattely 1
Affiliation  

Understanding the logic of plant natural product biosynthesis is important for three reasons: it guides the search for new natural products and pathways, illuminates the function of existing pathways in the context of host biology, and builds an enabling 'parts list' for plant and microbial metabolic engineering. In this review, we highlight the chemical themes that underlie a broad range of plant pathways, dividing pathways into two parts: scaffold-generating steps that draw on a limited set of chemistries, and tailoring reactions that produce a wide range of end products from a small number of common scaffolds.

中文翻译:

植物天然产物生物合成的化学逻辑。

了解植物天然产物生物合成的逻辑很重要,原因有以下三个:它指导寻找新的天然产物和途径,阐明宿主生物学背景下现有途径的功能,并为植物和微生物建立一个有利的“部分清单”代谢工程。在这篇综述中,我们强调了广泛植物途径背后的化学主题,将途径分为两部分:利用一组有限的化学物质产生支架的步骤,以及从植物中产生各种最终产物的定制反应。少数常见的脚手架。
更新日期:2014-04-14
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