In this review, we will summarize model organisms used by scientists in the laboratory, including Escherichia coli, yeast, Arabidopsis thaliana, nematodes, Drosophila, zebrafish, mice and other animals. We focus on the progress in research exploring different types of E. coli in the human body, and the specific molecular mechanisms by which they play a role in humans. First, we discuss the specific transcriptional regulation mechanism of E. coli in cell development, maturation, ageing and longevity, as well as tumorigenesis and development. Then, we discuss how the synthesis of some important substances in cells is regulated and how this affects biological behaviour. Understanding and applying these mechanisms, presumably, can greatly improve the quality of people's lives as well as increase their lifespan. For example, some E. coli can activate certain cells by secreting insulin-like growth factor-1, thus activating the inflammatory response of the body, while other E. coli can inactivate the immune response of the body by secreting toxic factors.

中文翻译：

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模式生物的转录调控：最新进展和临床意义。

在这篇综述中，我们将总结实验室中科学家使用的模型生物，包括大肠杆菌，酵母，拟南芥，线虫，果蝇，斑马鱼，小鼠和其他动物。我们专注于探索人类中不同类型大肠杆菌的研究进展，以及它们在人类中发挥作用的特定分子机制。首先，我们讨论了大肠杆菌在细胞发育，成熟，衰老和长寿以及肿瘤发生和发展中的特定转录调控机制。然后，我们讨论如何调控细胞中某些重要物质的合成，以及这如何影响生物学行为。大概理解并应用这些机制可以极大地改善人们的生活质量并延长他们的寿命。例如，一些E。