Purpose

In-stent restenosis (ISR) is related to local haemodynamics in the arteries after stent intervention. However, the haemodynamics of stents implanted into tapered vessels is rarely studied and remains unclear. This study aimed to study the haemodynamic performance of a stent in a tapered artery to reveal the haemodynamic differences between tapered and cylindrical stents after stent implantation and guide the stent selection for the treatment of coronary artery stenosis.

Methods

Cylindrical and tapered stents were implanted into the tapered arteries. A model of a cylindrical stent implanted into a cylindrical artery was established as the contrast model. Using the finite element method, the flow velocity and wall shear stress distribution of the three models were compared.

Results

At t₁, t₂, t₃ and t₄, the flow rate of the tapered artery with tapered stents (TT) after the implantation increased by 8.59, 3.80, 12.81 and 3.66%, respectively. In addition, the wall shear stress in the tapered arteries of TT was 23.48, 36.67, 13.00 and 8.06% higher than that of the tapered arteries with cylindrical stents (TC).

Conclusions

The implantation of a tapered stent in the tapered artery can effectively improve intravascular haemodynamics. The tapered stent allows the tapered artery to obtain better haemodynamics and reduces the probability of ISR.

中文翻译：

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锥形动脉介入锥形动脉的血流动力学研究。

目的

支架内介入治疗后，支架内再狭窄（ISR）与动脉局部血流动力学有关。然而，很少研究植入锥形血管的支架的血流动力学，目前仍不清楚。本研究旨在研究锥形动脉支架的血流动力学性能，以揭示锥形和圆柱形支架植入后的血流动力学差异，并指导选择支架治疗冠状动脉狭窄。

方法

将圆柱形和锥形支架植入锥形动脉中。建立植入到圆柱状动脉中的圆柱状支架的模型作为对比模型。使用有限元方法，比较了三个模型的流速和壁面剪应力分布。

结果

在t ₁，t ₂，t ₃和t _4时，植入后带有锥形支架（TT）的锥形动脉的流量分别增加了8.59、3.80、12.81和3.66％。此外，TT的锥形动脉壁剪切应力比带有圆柱形支架（TC）的锥形动脉高23.48、36.67、13.00和8.06％。

结论

在锥形动脉中植入锥形支架可以有效改善血管内血流动力学。锥形支架可使锥形动脉获得更好的血流动力学，并降低ISR的可能性。