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Carotid Artery Disease in Post‐Stroke Survivors and Effects of Enriched Environment on Stroke Pathology in a Mouse Model of Carotid Artery Stenosis
Neuropathology and Applied Neurobiology ( IF 4.0 ) Pub Date : 2019-05-23 , DOI: 10.1111/nan.12550
Y Hase 1 , T M Polvikoski 1 , M Ihara 2 , M Hase 1 , R Zafar 1 , W Stevenson 1 , L M Allan 1 , A Ennaceur 3 , K Horsburgh 4 , X Gallart-Palau 5 , S K Sze 5 , R N Kalaria 1
Affiliation  

Carotid artery disease (CAD) is an important risk factor for stroke. We first evaluated CAD and stroke pathology in elderly post‐stroke survivors. To simulate CAD, we assessed long‐term consequences of bilateral common carotid artery stenosis (BCAS) in mice and exposed them to environmental enrichment (EE).

中文翻译:

中风后幸存者的颈动脉疾病和丰富环境对颈动脉狭窄小鼠模型中风病理学的影响

颈动脉疾病(CAD)是中风的重要危险因素。我们首先评估了老年卒中后幸存者的 CAD 和卒中病理。为了模拟 CAD,我们评估了小鼠双侧颈总动脉狭窄 (BCAS) 的长期后果,并将它们暴露于富集环境 (EE) 中。
更新日期:2019-05-23
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