INTRODUCTION Postoperative delirium (POD) is a common complication in elderly surgical patients. Patients undergoing hip fractures surgery who are often characterized by advanced age could be particularly prone to suffering POD. We performed a meta-analysis to assess the association between POD and mortality in elderly patients undergoing hip fractures surgery. This meta-analysis included twenty-one cohort studies, and the pooled outcomes demonstrated that approximated one-fourth of patients undergoing hipfracture surgery would develop POD, and delirium increased the mortality in these patients. METHODS We searched PubMed, Embase, Web of Science, and Scopus for studies that investigated the effect of POD on mortality in elderly patients undergoing hip fracture surgery. Two reviewers independently selected studies, assessed quality, and extracted data. Statistical analyses were performed by STATA 14.0 and RevMan 5.3. Risk ratios (RRs) with 95% confidence intervals (CIs) were derived using random or fixed-effects model. RESULTS Twenty-one cohort studies enrolling a total of 6288 patients were included, and the pooled prevalence (95% CI) of POD was 28% (23-34%). POD was associated with an increase in perioperative mortality (30-day or in-hospital mortality) [12 studies, 3123 patients, relative risk (RR) (95% CI) 2.79 (1.97-3.93)], 6-month mortality [6 studies, 1673 patients, 2.51 (1.99-3.16)], 1-year mortality [6 studies, 1896 patients, 1.98 (1.62-2.41)], and more than 1-year mortality [8 studies, 1926 patients, 2.06 (1.60-2.64)]. CONCLUSIONS Our meta-analysis demonstrated that approximated one-fourth of patients undergoing hip fracture surgery would develop POD, and delirium increased the short-term and long-term mortality in these patients.

中文翻译：

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老年髋部骨折手术患者del妄与死亡率之间的关联：一项荟萃分析。

引言术后Post妄（POD）是老年手术患者的常见并发症。经常以高龄为特征的接受髋部骨折手术的患者特别容易患POD。我们进行了荟萃分析，以评估老年髋部骨折手术患者的POD与死亡率之间的关系。这项荟萃分析包括二十一项队列研究，汇总的结果表明，接受髋部骨折手术的患者中约有四分之一会出现POD，而ir妄会增加这些患者的死亡率。方法我们搜索了PubMed，Embase，Web of Science和Scopus，以研究POD对髋部骨折手术老年患者死亡率的影响。两名评论者独立选择研究，评估质量，并提取数据。统计分析由STATA 14.0和RevMan 5.3进行。使用随机或固定效应模型得出具有95％置信区间（CI）的风险比（RR）。结果共纳入21项队列研究，共纳入6288例患者，POD合并患病率（95％CI）为28％（23-34％）。POD与围手术期死亡率（30天或医院内死亡率）的增加相关[12个研究，3123例患者，相对危险度（RR）（95％CI）2.79（1.97-3.93）]，6个月死亡率[6研究，1673名患者，2.51（1.99-3.16）]，1年死亡率[6研究，1896名患者，1.98（1.62-2.41）]，以及1年以上死亡率[8研究，1926名患者，2.06（1.60- 2.64）]。结论我们的荟萃分析表明，接受髋部骨折手术的患者中约有四分之一会出现POD，