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Noncoding RNA Regulation of Dormant States in Evolutionarily Diverse Animals
The Biological Bulletin ( IF 1.6 ) Pub Date : 2019-10-01 , DOI: 10.1086/705484
Julie A. Reynolds

Dormancy is evolutionarily widespread and can take many forms, including diapause, dauer formation, estivation, and hibernation. Each type of dormancy is characterized by distinct features; but accumulating evidence suggests that each is regulated by some common processes, often referred to as a common “toolkit” of regulatory mechanisms, that likely include noncoding RNAs that regulate gene expression. Noncoding RNAs, especially microRNAs, are well-known regulators of biological processes associated with numerous dormancy-related processes, including cell cycle progression, cell growth and proliferation, developmental timing, metabolism, and environmental stress tolerance. This review provides a summary of our current understanding of noncoding RNAs and their involvement in regulating dormancy.

中文翻译:

进化多样性动物休眠状态的非编码 RNA 调控

休眠在进化上很普遍,可以采取多种形式,包括滞育、多尔形成、休眠和冬眠。每种类型的休眠都有不同的特点;但越来越多的证据表明,每个过程都受到一些共同过程的调控,通常被称为调控机制的共同“工具包”,其中可能包括调控基因表达的非编码 RNA。非编码 RNA,尤其是 microRNA,是众所周知的与许多休眠相关过程相关的生物过程的调节剂,包括细胞周期进程、细胞生长和增殖、发育时间、代谢和环境压力耐受性。本综述总结了我们目前对非编码 RNA 及其参与调节休眠的理解。
更新日期:2019-10-01
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