The 2014-2016 Ebola outbreak in West Africa was the largest of its kind with 11,000 deaths and approximately 28,637 affected cases. The aim of the study was to analyze the global situation after the Ebola outbreak including Ebola complications, vaccine development, lessons learned, financial losses, and disease preparedness. We searched in PubMed, Google, and Google Scholar by using keywords Ebola virus, Ebola vaccine development and Ebola virus transmission, the world after Ebola, financial losses by Ebola outbreak, and disease preparedness. Ebola virus disease is a complex disorder associated with gastrointestinal, hepatic, renal, respiratory, cardiovascular, and neurological complications. Ebola virus persisted in the semen of male infected patients for 470 to 565 days, and the chances of viral transmission by sexual contacts remained high even after patient recovery. There are several reports of extreme socioneuropsychological disorders in Ebola survivors and Ebola healthcare workers. There is no Food and Drug Administration-approved drug or vaccine for Ebola. Many research groups are working to develop a vaccine against Ebola by using different biotechnology techniques. Some vaccine candidates, including replicating vesicular stomatitis virus and Chimpanzee adenovirus-3, have entered phase III clinical trials and are expected to receive clinical licensing in coming years. The West African Ebola epidemic caused a financial loss of $6 billion in Africa and an additional global economic loss of more than $12 billion. After the Ebola epidemic, four global commissions were established for disease preparedness. A proposition was also forwarded to the World Health Organization for the establishment of the Centre for Emergency Preparedness and Response for the disease management. The devastating Ebola epidemic opened the window for disease preparedness to face any future disease epidemic.

中文翻译：

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埃博拉之后的世界：埃博拉并发症，疫苗开发，经验教训，经济损失和疾病预防概述。

2014-2016年西非埃博拉疫情是同类疫情中最大的一次，造成11,000人死亡，约28,637例感染病例。该研究的目的是分析埃博拉病毒爆发后的全球情况，包括埃博拉病毒并发症，疫苗开发，经验教训，经济损失和疾病预防。我们使用关键词埃博拉病毒，埃博拉疫苗开发和埃博拉病毒传播，埃博拉病毒之后的世界，埃博拉病毒爆发造成的经济损失以及疾病防备，在PubMed，Google和Google Scholar中进行了搜索。埃博拉病毒病是与胃肠，肝，肾，呼吸，心血管和神经系统并发症相关的复杂疾病。埃博拉病毒在男性感染患者的精液中持续了470至565天，而且即使患者康复后，通过性接触传播病毒的机会仍然很高。有几份关于埃博拉幸存者和埃博拉医护人员的严重社会神经心理疾病的报道。没有获得美国食品药品监督管理局批准的埃博拉病毒药物或疫苗。许多研究小组正在通过使用不同的生物技术技术来开发针对埃博拉的疫苗。一些候选疫苗，包括复制性水疱性口炎病毒和黑猩猩腺病毒3，已经进入III期临床试验，并有望在未来几年获得临床许可。西非埃博拉疫情在非洲造成60亿美元的财务损失，全球经济损失超过120亿美元。埃博拉疫情爆发后，成立了四个全球疾病预防委员会。还向世界卫生组织提出了一项建议，以建立疾病管理的应急准备和响应中心。毁灭性的埃博拉疫情为疾病预防面对任何未来的疾病流行打开了窗口。