Type 2 diabetes mellitus (T2DM) is the most common metabolic and multifactorial disease in which both genetic and environmental factors are involved. In diabetes, the defects in the cellular metabolism result in higher levels of free radicals. These radicals react with other vital cellular molecules, which are responsible in diabetes side effects and known as diabetic retinopathy (DR), a disease of the retina that results in impairment or loss of vision. In the present study, we investigated the expression of glutathione S-transferases class theta 1 (GSTT1) in type 2 DR subjects. Highly significant differences (P ≤ 0.05) were observed in GSST1 expression in DR patients compared with diabetic and control groups.

中文翻译：

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Gstt1在2型糖尿病视网膜病变患者中的表达。

2型糖尿病（T2DM）是最常见的代谢和多因素疾病，涉及遗传和环境因素。在糖尿病中，细胞代谢缺陷导致自由基水平升高。这些自由基与其他重要的细胞分子发生反应，这些分子与糖尿病的副作用有关，被称为糖尿病性视网膜病（DR），这是一种视网膜疾病，会导致视力受损或失明。在本研究中，我们调查了2型DR受试者中谷胱甘肽S-转移酶theta 1（GSTT1）的表达。与糖尿病组和对照组相比，DR患者的GSST1表达差异显着（P≤0.05）。