Epigenetics is the variation in organisms that occur by changes in gene expression, and it also occurs in the genetic code. The immune system diseases arise from primarily epigenetic changes of obscure etiology. The current studies demonstrate that a portion of the rearrangements are created by the association of epigenetic alterations. For example, acetylation of histones and methylation of DNA are accounted for. These adjustments in DNA likewise showed the impact in mouse models and immune system illnesses in human. Through this review, it could be reasoned that epigenetic tweaks might be a novel restorative approach against these maladies.

中文翻译：

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与组蛋白乙酰化和DNA甲基化有关的表观遗传修饰是免疫性疾病的关键因素。

表观遗传学是指由于基因表达变化而引起的生物体变异，也存在于遗传密码中。免疫系统疾病主要来自病因模糊的表观遗传变化。当前的研究表明，部分重排是由表观遗传学改变的关联造成的。例如，说明了组蛋白的乙酰化和DNA的甲基化。DNA的这些调节同样显示了对小鼠模型和人类免疫系统疾病的影响。通过这次审查，可以推断出表观遗传调整可能是针对这些疾病的一种新颖的修复方法。