The ability to adapt to changing internal and external conditions is a key feature of biological systems. Homeostasis refers to a regulatory process that stabilizes dynamic systems to counteract perturbations. In the nervous system, homeostatic mechanisms control neuronal excitability, neurotransmitter release, neurotransmitter receptors, and neural circuit function. The neuromuscular junction (NMJ) of Drosophila melanogaster has provided a wealth of molecular information about how synapses implement homeostatic forms of synaptic plasticity, with a focus on the transsynaptic, homeostatic modulation of neurotransmitter release. This review examines some of the recent findings from the Drosophila NMJ and highlights questions the field will ponder in coming years.

中文翻译：

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果蝇神经肌肉连接功能的稳态控制。

适应变化的内部和外部条件的能力是生物系统的关键特征。稳态是指一种​​调节过程，可稳定动态系统以抵消干扰。在神经系统中，稳态机制控制神经元兴奋性，神经递质释放，神经递质受体和神经回路功能。黑腹果蝇的神经肌肉接头（NMJ）已经提供了大量有关突触如何实现稳态形式的突触可塑性的分子信息，重点是神经递质释放的突触，稳态调节。这篇评论检查了果蝇NMJ最近的一些发现，并着重指出了该领域在未来几年中将要思考的问题。