CRYPTOCHROMES (CRYs) are structurally related to ultraviolet (UV)/blue-sensitive DNA repair enzymes called photolyases but lack the ability to repair pyrimidine dimers generated by UV exposure. First identified in plants, CRYs have proven to be involved in light detection and various light-dependent processes in a broad range of organisms. In Drosophila, CRY's best understood role is the cell-autonomous synchronization of circadian clocks. However, CRY also contributes to the amplitude of circadian oscillations in a light-independent manner, controls arousal and UV avoidance, influences visual photoreception, and plays a key role in magnetic field detection. Here, we review our current understanding of the mechanisms underlying CRY's various circadian and noncircadian functions in fruit flies.

中文翻译：

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果蝇隐色：蓝色的变化。

CRYPTOCHROMES（CRYs）在结构上与称为光裂解酶的紫外线（UV）/蓝光敏感DNA修复酶有关，但缺乏修复因UV暴露而产生的嘧啶二聚体的能力。CRYs最早在植物中被鉴定出来，已被证明参与多种生物中的光检测和各种依赖光的过程。在果蝇中，CRY最能理解的作用是昼夜节律的细胞自主同步。但是，CRY还以与光无关的方式增加了生物钟振荡的幅度，控制了唤醒和紫外线的回避，影响了视觉光接收，并在磁场检测中起着关键作用。在这里，我们回顾我们目前对果蝇中CRY的各种昼夜和非昼夜功能的潜在机制的理解。