The 2017–2018 flu season is considered to be one of the most severe, with numerous influenza outbreaks worldwide. In an infectious disease hospital of Qinhuangdao, air samples were collected daily from outpatient hall, clinical laboratory, fever clinic, children's ward (Children's Ward I/Children's Ward II), and adult ward during 23–29 January 2018 (peak flu activity) and 9–15 April 2018 (low flu activity). The air samples were collected with SLC-SiOH magnetic beads using impingement samplers. Real-time PCR assay was used to detect the RNA of airborne influenza (IFVA and IFVB) in the 91 collected aerosol samples. The results indicated that the air samples collected from the children's wards, adult ward and fever clinic were detected with airborne influenza viruses. However, the samples collected from outpatient hall and clinical laboratory were absence of influenza viruses. In addition, the subtypes of pH1N1/IFVA, H3N2/IFVA, yamagata/IFVB, and victoria/IFVB were detected among the samples with positive IFVA and IFVB. Notably, a new developed subtype of pH1N1 (an epidemic in 2018) was detected in the aerosol samples. In summary, this study profiled the distribution of airborne influenza in an infectious hospital in Qinhuangdao during 2017–2018 flu season. Patients infected with influenza could release airborne particles containing the virus into their environment. Healthcare workers and visitors in those places might have frequent exposure to airborne influenza virus. Therefore, we recommend some protective measures such as air disinfection and mask wearing to prevent and control the transmission of airborne influenza in hospital.

中文翻译：

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2017-2018年流感季节期间，秦皇岛一家医院的流感病毒通过空气传播。

2017-2018年流感季节被认为是最严重的季节之一，全球范围内爆发了许多流感。在秦皇岛一家传染病医院，2018年1月23日至29日期间，每天从门诊大厅，临床实验室，发烧诊所，儿童病房（儿童病房I /儿童病房II）和成人病房收集空气样本（高峰流感活动）， 2018年4月9日至15日（低流感活动）。使用冲击采样器用SLC-SiOH磁珠收集空气样本。实时荧光定量PCR检测91份气溶胶样品中的空气传播流感RNA（IFVA和IFVB）。结果表明，从儿童病房，成人病房和发烧门诊收集的空气样本中检出了空气传播的流感病毒。然而，从门诊和临床实验室收集的样本中没有流感病毒。另外，在IFVA和IFVB阳性的样品中检测到pH1N1 / IFVA，H3N2 / IFVA，山形/ IFVB和维多利亚/ IFVB的亚型。值得注意的是，在气溶胶样品中检测到一种新开发的pH1N1亚型（2018年流行）。总而言之，本研究概述了2017-2018年流感季节期间秦皇岛一家传染病医院的空气传播流感的分布。感染流感的患者可以将含有病毒的空气传播颗粒释放到他们的环境中。这些地方的医护人员和访客可能经常接触空气传播的流感病毒。因此，