By examining the literature concerning early intervention with antipsychotic medications, and how it affects long-term morbidity, this article will review the concept that early intervention with antipsychotic medications improves the long-term course of schizophrenia. It also looks at the potential long-term effects of discontinuing antipsychotic medications early in the course of schizophrenia. It appears that early intervention with antipsychotic medications decreases some of the long-term morbidity associated with schizophrenia. Some of the implications of this finding are discussed in the context of both clinical practice and clinical research.

中文翻译：

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早期和持续干预对精神分裂症长期发病率的影响。


通过研究有关抗精神病药物早期干预及其如何影响长期发病率的文献，本文将回顾抗精神病药物早期干预可改善精神分裂症长期病程的概念。它还着眼于在精神分裂症病程早期停止抗精神病药物的潜在长期影响。抗精神病药物的早期干预似乎可以降低与精神分裂症相关的一些长期发病率。在临床实践和临床研究的背景下讨论了这一发现的一些含义。