In recent years, discourses around “personalized,” “stratified,” and “precision” medicine have proliferated. These concepts broadly refer to the translational potential carried by new data-intensive biomedical research modes. Each describes expectations about the future of medicine and healthcare that data-intensive innovation promises to bring forth. The definitions and uses of the concepts are, however, plural, contested and characterized by diverse ideas about the kinds of futures that are desired and desirable. In this paper, we unpack key disputes around the “personalized,” “stratified,” and “precision” terms, and map the epistemic, political and economic contexts that structure them as well as the different roles attributed to patients and citizens in competing future imaginaries. We show the ethical and value baggage embedded within the promises that are manufactured through terminological choices and argue that the context and future-oriented nature of these choices helps to understanding how data-intensive biomedical innovations are made socially meaningful.

中文翻译：

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充满争议的未来：展望“个性化”、“分层”和“精准”医学

近年来，围绕“个性化”、“分层”和“精准”医学的讨论激增。这些概念广义上指的是新的数据密集型生物医学研究模式所带来的转化潜力。每个都描述了对数据密集型创新有望带来的医学和医疗保健未来的期望。然而，这些概念的定义和使用是多元的、有争议的，并且其特点是关于期望和理想的未来种类的不同想法。在本文中，我们解开了围绕“个性化”、“分层”和“精确”术语的关键争议，并绘制了构成这些术语的认知、政治和经济背景，以及患者和公民在未来竞争中的不同角色。想象。我们展示了通过术语选择制造的承诺中嵌入的道德和价值包袱，并认为这些选择的背景和面向未来的性质有助于理解数据密集型生物医学创新如何具有社会意义。