Sensory neurons provide organisms with data about the world in which they live, for the purpose of successfully exploiting their environment. The consequences of sensory perception are not simply limited to decision-making behaviors; evidence suggests that sensory perception directly influences physiology and aging, a phenomenon that has been observed in animals across taxa. Therefore, understanding the neural mechanisms by which sensory input influences aging may uncover novel therapeutic targets for aging-related physiologies. In this review, we examine different perceptive experiences that have been most clearly linked to aging or age-related disease: food perception, social perception, time perception, and threat perception. For each, the sensory cues, receptors, and/or pathways that influence aging as well as the individual or groups of neurons involved, if known, are discussed. We conclude with general thoughts about the potential impact of this line of research on human health and aging.

中文翻译：

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通过感知镜头驱动机体衰老的神经元机制。

感觉神经元为有机体提供有关它们所生活的世界的数据，目的是成功地利用它们的环境。感官知觉的后果不仅限于决策行为；有证据表明，感官知觉直接影响生理和衰老，这一现象已在动物中观察到。因此，了解感觉输入影响衰老的神经机制可能会发现衰老相关生理学的新治疗靶点。在这篇综述中，我们研究了与衰老或与年龄相关的疾病最明显相关的不同感知体验：食物感知、社会感知、时间感知和威胁感知。对于每一个，感觉线索，感受器，和/或影响衰老的途径以及所涉及的个体或神经元组（如果已知）进行了讨论。最后，我们对这一研究方向对人类健康和衰老的潜在影响进行了总体思考。