Abstract Carboxylic acid anions intercalated layered double hydroxides are currently gaining increasing interest due to their potential applications in pharmaceutical field for controlled drug release in novel tunable drug delivery systems. In this work different aliphatic carboxylic acid anions were intercalated into the interlayers of commercial as well as synthetically prepared layered double hydroxides, through a novel microwave mediated melt reaction approach. The volumetric nature of microwave dielectric heating was exploited in order to rapidly heat the intimate mixture of the lamellar inorganic precursor and the appropriate organic acid, at the melting temperature of the particular mono-or dicarboxylic acid used, reaching the intercalation in approximately two hours treatment.

中文翻译：

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羧酸阴离子嵌入层状双氢氧化物的微波辅助熔融反应法

摘要 羧酸阴离子嵌入层状双氢氧化物由于其在制药领域的潜在应用，在新型可调药物递送系统中控制药物释放，目前越来越受到关注。在这项工作中，通过一种新型的微波介导的熔融反应方法，不同的脂肪族羧酸阴离子被插入到商业和合成制备的层状双氢氧化物的夹层中。利用微波介电加热的体积特性，在所用的特定单羧酸或二羧酸的熔化温度下，快速加热层状无机前体和适当有机酸的紧密混合物，在大约两小时的处理中达到插层.