West Nile virus (WNV) is an RNA flavivirus transmitted through a mosquito vector. In 2018 Nebraska reported 242 cases, the highest incidence of WNV since 2003. This included 119 neuroinvasive cases (49%) and 11 deaths (4.5%) (DHHS 2018). Clinical presentation ranges from uncomplicated symptoms including fever, headache, and myalgias to neuroinvasive disease characterized by meningoencephalitis, flaccid paralysis, and other neurologic manifestations. Neuroinvasive WNV usually occurs in elderly and immunocompromised individuals, and ocular involvement is often not detected until later in the disease course. We describe a case of neuroinvasive WNV presenting with uveomeningitis in a young and otherwise healthy patient.

中文翻译：

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健康的年轻男性的葡萄膜神经系统综合征：西尼罗河病毒的异常表现。

西尼罗河病毒（WNV）是通过蚊子载体传播的RNA黄病毒。内布拉斯加州在2018年报告了242例病例，是自2003年以来最高的WNV发病率。这包括119例神经侵袭病例（49％）和11例死亡（4.5％）（DHHS 2018）。临床表现范围从包括发烧，头痛和肌痛在内的简单症状到以脑膜脑炎，松弛性麻痹和其他神经系统表现为特征的神经浸润性疾病。神经侵入性WNV通常发生在年老且免疫功能低下的人中，并且直到疾病进程的后期才经常发现眼部受累。我们描述了一个年轻和其他健康患者伴葡萄膜炎的神经侵袭性NNV病例。